As
Originally
Printed in
Tanning
Trends
magazine
January 2002
Determined
To Defend
Vitamin D
Dr. Michael
Holick took
a big step
forward in
2001 in
making the
case that
sun-induced
vitamin D is
critical to
human
health.
He stood
there,
again, on
the ballroom
stage in
Nashville in
front of
hundreds of
indoor
tanning
facility
operators,
for the
sixth year
in a row
playing a
major part
in Smart
Tan's
educational
conference.
He is Boston
University's
Dr. Michael
Holick -
perhaps the
world's
leading
researcher
touting the
belief that
humanity, in
its recent
obsession
over fitness
and
preventative
medicine,
has
overlooked
the
importance
of one
particular
vitamin -
the human
hormone
sometimes
called "The
Sunshine
Vitamin."
We know it
as vitamin
D.
So Holick
stood there
again Oct.
25 in
Nashville,
reviewing
what he has
deemed "The
Good, The
Bad and The
Ugly" about
ultraviolet
light. Many
in the
audience
have heard
him speak
several
times before
- three,
four or even
five times.
For any
other
speaker,
that's a
recipe for
yawns. But
the indoor
tanning
industry
soaks in
Holick's
material
each year,
and Holick
pours an
increasing
amount of
energy and
excitement
into his
talks.
And this
year the
tanning
industry had
something to
be excited
about.
Holick is on
the verge of
publishing
the results
of research
the tanning
industry
funded,
confirming
some
long-believed
theories
about indoor
tanning and
vitamin D
production.
Call it the
first giant
step in the
tanning
industry's
new effort
to mount
data in
support of
the positive
effects of
ultraviolet
light.
"We think
that in
general the
population
is in risk
of vitamin D
deficiency
chronically
at all
ages,"
Holick said.
"Only by
having
adequate
exposure to
sunlight or
taking much
more vitamin
D will you
satisfy your
vitamin D
requirements."
Holick is
the director
of the
General
Clinical
Research
Center at
the Boston
University
School of
Medicine - a
lofty,
credible
position in
the research
community.
He also
directs the
school's
Vitamin D,
Skin and
Bone Center.
He is
perhaps the
world's most
respected
photobiologist
who believes
that the
benefits of
regular sun
exposure
received in
a
non-burning
fashion
outweigh the
risks.
The lack of
vitamin D,
and what
that
deficiency
can lead to,
is Holick's
main
concern.
Bone
diseases
such as
osteoporosis
and
osteomalacia
are linked
to vitamin D
deprivation,
and
researchers
this year
have
uncovered
the
mechanism by
which
vitamin D
plays a role
in the
prevention
of breast,
colon and
prostate
cancers.
That
discovery
has Holick
very
excited.
"The
dermatology
community is
beginning to
rethink this
issue," he
explained.
"It has been
a long and
tough battle
in trying to
have them
appreciate
that there
are some
beneficial
effects to
the tanning
process and
being
exposed to
sunlight."
To make his
case, Holick
had to
attack some
pretty
established
preconceived
notions
about
ultraviolet
light. "I
think many
dermatologists
don't
understand
it. They
have
pseudo-information,
and as a
result it is
easy for
them to
stick their
heads in the
sand and say
that 'That
is our
policy: No
exposure to
sunlight and
always wear
sunscreen.
End of
story.' They
don't
appreciate
the
potential
health
consequences
of that."
But now he
believes he
is turning
the corner
in getting
people to
recognize
his work and
the work of
others who
believe in
the positive
effects of
sunlight.
The U.S.
Food and
Drug
Administration,
for
instance, is
watching his
work very
closely. "I
think that
more of the
research
dermatologists
- those that
are really
in the
forefront of
dermatology
- are
finally
getting the
message that
I have been
trying to
get across
for a long
time that
maybe there
is in fact a
benefit. And
that we
really need
to look at
both sides
of the coin,
that it is
not simply
black and
white that
you should
not have any
exposure to
sunlight or
tanning bed
radiation."
Holick's New
Research
Dr. Michael
Holick
presented
preliminary
data on
three
studies he
completed
this year at
Smart Tan's
educational
conference
at the ITA
Indoor
Tanning
World Expo.
Holick first
proposed
these
studies in
1999 and
approached
the tanning
industry for
financial
support for
the project.
Smart Tan
did much of
the early
legwork, and
funded 38
percent of
the project.
The Indoor
Tanning
Association
- formed in
1999 to fund
research and
promotional
efforts for
the industry
- made
completion
of the
project
funding
possible, by
funding 62
percent of
the effort.
"Tanning bed
exposure has
both
benefits and
potential
harmful
effects if
not used
properly,"
Holick says.
"The concept
that Smart
Tan is
trying to
get across
is a very
good one.
That is,
that if you
want to tan,
you should
tan properly
and
intelligently
and you
should
never, never
burn."
Here is a
glimpse at
what Holick
will be
publishing
in
peer-reviewed
medical
journals in
the coming
months from
research
conducted
with funding
from ITA and
Smart Tan:
1. UV Light
Treats
Osteoporosis
Holick has
submitted a
paper to the
Journal of
Gastroneurology
summarizing
a case study
completed
with funding
from ITA and
Smart Tan.
The study is
of a
61-year-old
woman who
came to his
Vitamin D
clinic who
was severely
vitamin D
deficient
and showed
signs of
significant
bone decay
consistent
with
osteoporosis.
"It was so
severe when
she came to
my office
she couldn't
sit down,
she was in
tears
because all
her bones
ached so
much,"
Holick
explained.
"So what do
you do?
Tanning beds
to the
rescue."
Using the
tanning
equipment
donated to
Holick by
Tan America
and puretan
as part of
the ITA
study,
Holick
exposed the
woman three
times a week
to tanning
bed light,
following
the
recommended
exposure
schedule for
her skin
type. The
woman's
condition
improved
significantly.
"The bone
pain over
several
months
gradually
dissolved,
and the
vitamin D
level
increased by
700 percent,
just by
simply being
exposed to
tanning bed
radiation,"
Holick
explained.
Osteoporosis
is a greater
problem than
many people
realize.
More than 25
million
Americans
suffer from
osteoporosis,
20 million
of whom are
women. This
debilitating
disease
usually
leaves a
person
stooped
over, and
their
activity is
severely
limited.
Vitamin D
deficiency
also can
cause
osteomalacia,
a
mineralization
defect that
causes
intense
pain.
However,
vitamin D
alone isn't
enough for
good bone
health;
calcium
helps the
body absorb
the vitamin.
Dr. Holick's
recipe:
Calcium plus
vitamin D
plus
exercise
equals good
bone health.
Without
vitamin D,
the body can
only absorb
10 to 15
percent of
the calcium
it does when
healthy
vitamin D
levels are
present.
Holick's
case study
should be
published in
the next few
months.
2. Tanning
Bed Light Is
a Good
Source of
Vitamin D
For years
Holick has
talked about
the theory
of "Vitamin
D Winter" -
a term he
coined
describing
the fact
that there
is not
sufficient
UVB outdoors
from
November
through
March in the
Northeast
for a person
to even
produce
vitamin D.
This may
explain why
so much of
the
population
is vitamin D
deficient.
In 1998,
Holick
published a
paper in the
medical
journal The
Lancet
showing that
41 percent
of hospital
patients at
Massachusetts
General
Hospital
were vitamin
D deficient.
Since that
time, with
funding from
ITA and
Smart Tan,
Holick has
compiled
data on
another
group of
chronically
unexposed
people: his
own medical
students,
whose
studies
leave them
little time
outdoors at
all. "These
are people
who never
see the
light of
day," Holick
explained.
Sure enough,
41 percent
of his
medical
students
were vitamin
D deficient.
But, upon
exposure to
the tanning
beds in
Holick's
lab, the
condition
was
corrected.
Holick will
be
publishing a
paper on
this data in
the near
future. "It
will show
that tanning
is a very
effective
way to
maintain
your vitamin
D status,"
Holick said.
His work
with the
medical
students
also
produced
some other
results.
Using a
flash
spectrometer
purchased by
Smart Tan,
Holick was
able to
"measure"
and chart
the progress
of the
students'
tans. Two
hours after
tanning, the
group showed
immediate
pigment
darkening -
a 2-3
percent
increase in
pigmentation.
Within 48
hours,
melanin
content
increased up
to 40
percent.
Holick
believes
there may be
a link
between
melanin
production
and vitamin
D
production.
This data
will help
him explore
that theory.
3. Studying
UV Light and
DNA
Studying the
intercellular
activity of
tanned skin
cells is a
field Holick
is
pioneering.
In the mid
1990s
California
Tan
purchased a
specialized
$100,000
confocal
microscope
for Holick
that helped
him gaze
into
individual
live skin
cells as
they tanned
and explore
this field
for the
first time.
Now ITA and
Smart Tan
have leased
Holick a
$100,000
genetic
testing
machine that
will help
him measure
gene
expression,
DNA repair
and chart
the role
vitamin D
plays in the
regulation
of cell
growth. He
is closely
monitoring a
substance
known as TGF
beta which
is believed
to regulate
cell growth.
This is
particularly
important,
given work
that now
suggests
vitamin D
may play a
role in the
prevention
of breast,
colon and
prostate
cancers.
"We are now
in the
process of
trying to
understand
how that
impacts skin
health and
disease,"
Holick said.
"We are now
in the
process of
analyzing
our data."
Clearing the
Anti-Cancer
Picture
Holick and
other
photobiologists
are excited
about new
work this
year that
appears to
have
unlocked the
puzzle of
why sunlight
exposure is
linked to
lower risks
of many
internal
cancers. The
research
community
has known
since the
1940s that
prostate,
colon and
breast
cancers are
less common
in sunny
parts of the
world. While
vitamin D
was
suspected to
play a role
in this,
nobody
understood
exactly why
until this
year.
Vitamin D
produced
from sun
exposure is
activated in
the body in
the liver
and kidneys.
"The
activated
form does
something
else very
important.
It tells
your cells
to grow
properly.
Activated
Vitamin D
inhibits
cancer
growth."
But
researchers
this year
discovered
something
new that
explains
this
relationship.
"Breast,
colon and
prostate
cells all
activate
vitamin D.
That is a
new
concept." We
now realize
that not
only does
your kidney
make it -
but your
colon,
breast and a
lot of other
tissues make
it as well,
This is a
likely
explanation
for the
sun-cancer
connection."
That has
Holick
wondering if
recommendations
for vitamin
D intake -
which are
based on
maintaining
bone health
- should be
reviewed.
"There may
be two
levels of
vitamin D
deficiency -
one for bone
health, and
one for
cellular
health," he
explained.
Turning to
the Sun
Holick's
work in the
mid 1990s
showed that
there is no
reliable
source of
vitamin D in
our diets,
that vitamin
D levels
reported on
milk cartons
are
overestimated
half of the
time and
that 15-20
percent of
milk has no
vitamin D
content at
all. That
leaves sun
exposure and
vitamin
supplementation
as the only
alternatives.
Since it is
not
reasonable
to assume
that the
entire
population
will turn to
vitamin
supplementation,
that puts
sunshine
back into
play as an
important
source of
this
important
vitamin.
"With
adequate
exposure to
sunlight,
dietary
vitamin D
becomes
unnecessary.
It is
remarkable
how exposure
to sunlight
a few times
a week can
reduce the
risk of
osteoporosis,
osteomalacia,
muscle
weakness,
fractures
and maybe
some of the
common
cancers, but
also induce
a sense of
well-being."
Holick wrote
in an
article in
The Lancet
earlier this
year.
And Holick
is
determined
to get that
message to
the masses.
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